Invention Grant
US08758769B2 Composition for preventing and treating acetaminophen inducing liver injury comprising the protein extract from Porphyra yezoensis
有权
用于预防和治疗诱导肝损伤的对乙酰氨基酚的组合物，其包含来自紫菜属（Porphyra yezoensis）的蛋白质提取物
- Patent Title: Composition for preventing and treating acetaminophen inducing liver injury comprising the protein extract from Porphyra yezoensis
- Patent Title (中): 用于预防和治疗诱导肝损伤的对乙酰氨基酚的组合物，其包含来自紫菜属（Porphyra yezoensis）的蛋白质提取物
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Application No.: US12083195Application Date: 2007-08-28
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Publication No.: US08758769B2Publication Date: 2014-06-24
- Inventor: Taek-Jeong Nam , Mi-Jin Kwon , Hye-Jung Hwang
- Applicant: Taek-Jeong Nam , Mi-Jin Kwon , Hye-Jung Hwang
- Applicant Address: KR Busan
- Assignee: Pukyong National University Industry Academic Cooperation Foundation
- Current Assignee: Pukyong National University Industry Academic Cooperation Foundation
- Current Assignee Address: KR Busan
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: KR10-2006-0107896 20061102
- International Application: PCT/KR2007/004132 WO 20070828
- International Announcement: WO2008/054057 WO 20080508
- Main IPC: A61K36/02
- IPC: A61K36/02 ; A61K8/97
Abstract:
Disclosed is a composition for preventing and treating acetaminophen induced liver injury including the protein extracted from Porphyra yezoensis. The protein(s), separated and purified from hot water extracts of Porphyra yezoensis, having the molecular weight of 14 kDa measured by sodium dodecyl sulfate polyacrylamide gel electrophoresis, has an excellent effect for inhibiting the oxidative injury of liver tissue and cell apoptosis of liver cells induced by acetaminophen.
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