Invention Grant
- Patent Title: Compositions and methods for treatment
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Application No.: US13011775Application Date: 2011-01-21
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Publication No.: US08758776B2Publication Date: 2014-06-24
- Inventor: Johan Oslob , Wang Shen , Kenneth Barr , Min Zhong
- Applicant: Johan Oslob , Wang Shen , Kenneth Barr , Min Zhong
- Applicant Address: US CA Brisbane
- Assignee: Sarcode Bioscience Inc.
- Current Assignee: Sarcode Bioscience Inc.
- Current Assignee Address: US CA Brisbane
- Agency: Troutman Sanders LLP
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K31/47
Abstract:
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists.
Public/Granted literature
- US20110165229A1 Compositions and Methods for Treatment Public/Granted day:2011-07-07
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