Invention Grant
US08758997B2 Method for detecting polymorphism at nucleotide position-1639 of VKORC1 gene, and nucleic acid probe and kit therefor
有权
在VKORC1基因的核苷酸位置-1639处检测多态性的方法，以及核酸探针及其试剂盒
- Patent Title: Method for detecting polymorphism at nucleotide position-1639 of VKORC1 gene, and nucleic acid probe and kit therefor
- Patent Title (中): 在VKORC1基因的核苷酸位置-1639处检测多态性的方法，以及核酸探针及其试剂盒
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Application No.: US13150680Application Date: 2011-06-01
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Publication No.: US08758997B2Publication Date: 2014-06-24
- Inventor: Mariko Komori
- Applicant: Mariko Komori
- Applicant Address: JP Kyoto
- Assignee: Arkray, Inc.
- Current Assignee: Arkray, Inc.
- Current Assignee Address: JP Kyoto
- Agency: Morgan, Lewis & Bockius LLP
- Priority: JP2010-126306 20100601
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04
Abstract:
A probe for detecting a polymorphism at position −1639 of the VKORC1 gene, the probe comprising an oligonucleotide having a nucleotide sequence having a length of 10 to 50 nucleotides, which nucleotide sequence comprises the nucleotides 80 to 89 of SEQ ID NO:1 or 2 and has a homology to SEQ ID NO:1 or 2 except that the nucleotide corresponding to the nucleotide at position 80 in SEQ ID NO:1 or 2 is cytosine, which nucleotide corresponding to the nucleotide at position 80 is labeled with a fluorescent dye.
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