Invention Grant
- Patent Title: Humanized anti-CD47 antibody
- Patent Title (中): 人源化抗CD47抗体
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Application No.: US13329658Application Date: 2011-12-19
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Publication No.: US08759025B2Publication Date: 2014-06-24
- Inventor: Yasufumi Kikuchi , Shinsuke Uno , Yasuko Kinoshita , Shigeyuki Iijima , Naoshi Fukushima , Masayuki Tsuchiya
- Applicant: Yasufumi Kikuchi , Shinsuke Uno , Yasuko Kinoshita , Shigeyuki Iijima , Naoshi Fukushima , Masayuki Tsuchiya
- Applicant Address: JP Tokyo
- Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2003-381406 20031111
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12N15/87 ; C12N5/02 ; C12N5/20 ; C12N1/20 ; C12N15/00 ; C07H21/04
Abstract:
The present invention relates to humanized antibodies binding to CD47; diabodies binding to human CD47, characterized in that a disulfide bond exists between diabody-forming fragments; genes encoding any one of said antibodies; vectors containing said genes; host cells containing said vectors; processes for preparing antibodies comprising the step of culturing said host cells; and therapeutic agents for hematological disorders comprising said antibodies.
Public/Granted literature
- US20120156724A1 HUMANIZED ANTI-CD47 ANTIBODY Public/Granted day:2012-06-21
Information query
