Invention Grant
- Patent Title: Production and purification of IL-29
- Patent Title (中): 生产和纯化IL-29
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Application No.: US13720363Application Date: 2012-12-19
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Publication No.: US08759027B2Publication Date: 2014-06-24
- Inventor: Bruce L. Zamost , Geoffrey F. Lee , Robert M. Dedinsky
- Applicant: ZymoGenetics, Inc.
- Applicant Address: US WA Seattle
- Assignee: ZymoGenetics, Inc.
- Current Assignee: ZymoGenetics, Inc.
- Current Assignee Address: US WA Seattle
- Agent Bing Hai
- Main IPC: C12N15/24
- IPC: C12N15/24 ; C12P21/02 ; C07K14/54
Abstract:
The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
Public/Granted literature
- US20130143270A1 PRODUCTION AND PURIFICATION OF IL-29 Public/Granted day:2013-06-06
Information query
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