Invention Grant
- Patent Title: DNA polymerases with improved activity
- Patent Title (中): 具有改善活性的DNA聚合酶
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Application No.: US13706107Application Date: 2012-12-05
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Publication No.: US08759063B2Publication Date: 2014-06-24
- Inventor: Keith Bauer , Thomas W. Myers , Shawn Suko
- Applicant: Roche Molecular System, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Molecular Systems, Inc.
- Current Assignee: Roche Molecular Systems, Inc.
- Current Assignee Address: US CA Pleasanton
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; G01N33/535 ; C12N15/10

Abstract:
Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
Public/Granted literature
- US20130149747A1 DNA POLYMERASES WITH IMPROVED ACTIVITY Public/Granted day:2013-06-13
Information query
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