Invention Grant
- Patent Title: Long-acting coagulation factors and methods of producing same
- Patent Title (中): 长效凝血因子及其制备方法
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Application No.: US13372540Application Date: 2012-02-14
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Publication No.: US08759292B2Publication Date: 2014-06-24
- Inventor: Udi Eyal Fima , Gili Hart
- Applicant: Udi Eyal Fima , Gili Hart
- Applicant Address: US DE Wilmington
- Assignee: Prolor Biotech, LLC
- Current Assignee: Prolor Biotech, LLC
- Current Assignee Address: US DE Wilmington
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Agent Mark S. Cohen
- Main IPC: A61K38/36
- IPC: A61K38/36 ; C07K1/00 ; C07K14/745
Abstract:
Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using and producing same are also disclosed.
Public/Granted literature
- US20120208759A1 LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME Public/Granted day:2012-08-16
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