Invention Grant
US08759318B2 Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections
失效
用于治疗病毒感染的鸟苷核苷化合物的氨基磷酸衍生物
- Patent Title: Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections
- Patent Title (中): 用于治疗病毒感染的鸟苷核苷化合物的氨基磷酸衍生物
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Application No.: US13143098Application Date: 2010-01-11
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Publication No.: US08759318B2Publication Date: 2014-06-24
- Inventor: Stanley Chamberlain , Jeff Hutchins , Karolina Madela , Christopher McGuigan , John Vernachio , Mohamed Aljarah , Arnaud Gilles
- Applicant: Stanley Chamberlain , Jeff Hutchins , Karolina Madela , Christopher McGuigan , John Vernachio , Mohamed Aljarah , Arnaud Gilles
- Applicant Address: US GA Alpharetta GB Cardiff
- Assignee: Inhibitex, Inc.,University College Cardiff Consultants Limited
- Current Assignee: Inhibitex, Inc.,University College Cardiff Consultants Limited
- Current Assignee Address: US GA Alpharetta GB Cardiff
- Agency: Stites & Harbison, PLLC.
- Agent B. Aaron Schulman
- International Application: PCT/US2010/020632 WO 20100111
- International Announcement: WO2010/081082 WO 20100715
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70
Abstract:
Phosphoramidate compounds derived from guanine bases having enhanced therapeutic potency are provided, and these compounds in particular have enhanced potency with respect to treatment of viral infections, such as hepatitis C virus. Pharmaceutical compositions, methods of preparing the compounds, and methods of using the compounds and compositions to treat viral infections are also provided.
Public/Granted literature
- US20120052046A1 Phosphoramidate Derivatives of Guanosine Nucleoside Compunds for Treatment of Viral Infections Public/Granted day:2012-03-01
Information query
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