Invention Grant
US08759327B2 Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
有权
纤溶酶原激活物抑制剂-1抑制剂及其用于调节脂质代谢的方法
- Patent Title: Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
- Patent Title (中): 纤溶酶原激活物抑制剂-1抑制剂及其用于调节脂质代谢的方法
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Application No.: US12104409Application Date: 2008-04-16
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Publication No.: US08759327B2Publication Date: 2014-06-24
- Inventor: Daniel A. Lawrence , Dudley Strickland , Jacqueline Cale , Enming J. Su , Cory Emal , Mark Warnock
- Applicant: Daniel A. Lawrence , Dudley Strickland , Jacqueline Cale , Enming J. Su , Cory Emal , Mark Warnock
- Applicant Address: US MI Ann Arbor US MD Baltimore US MI Ypsilanti
- Assignee: The Regents of the University of Michigan,University of Maryland, Baltimore,Eastern Michigan University
- Current Assignee: The Regents of the University of Michigan,University of Maryland, Baltimore,Eastern Michigan University
- Current Assignee Address: US MI Ann Arbor US MD Baltimore US MI Ypsilanti
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: G01N33/566
- IPC: G01N33/566 ; A61K31/60 ; A61K31/235 ; A61K31/192 ; A61K31/195 ; A61K31/352 ; C07D317/04 ; C07C69/773 ; C07C62/04 ; C07C333/02 ; A61P3/10 ; A61P9/10 ; A61P35/00
Abstract:
The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
Public/Granted literature
- US20090011055A1 Plasminogen Activator Inhibitor-1 Inhibitors And Methods Of Use Thereof To Modulate Lipid Metabolism Public/Granted day:2009-01-08
Information query
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