Invention Grant
- Patent Title: Gamma secretase modulators
- Patent Title (中): 伽玛分泌酶调节剂
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Application No.: US13140987Application Date: 2009-12-18
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Publication No.: US08759337B2Publication Date: 2014-06-24
- Inventor: Theodros Asberom , Xianhai Huang , Zhaoning Zhu , John W. Clader , Dmitri A. Pissarnitski , Hubert B. Josien , Hongmei Li
- Applicant: Theodros Asberom , Xianhai Huang , Zhaoning Zhu , John W. Clader , Dmitri A. Pissarnitski , Hubert B. Josien , Hongmei Li
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; John C. Todaro
- International Application: PCT/US2009/068684 WO 20091218
- International Announcement: WO2010/075203 WO 20100701
- Main IPC: A61K31/553
- IPC: A61K31/553 ; C07D498/04
Abstract:
This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (Chemical formula should be inserted here as it appears on abstract in paper form). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).
Public/Granted literature
- US20110294784A1 GAMMA SECRETASE MODULATORS Public/Granted day:2011-12-01
Information query
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