Invention Grant
US08759341B2 Bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives and uses thereof
有权
双环和三环吲唑取代的1,4-二氢吡啶衍生物及其用途
- Patent Title: Bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives and uses thereof
- Patent Title (中): 双环和三环吲唑取代的1,4-二氢吡啶衍生物及其用途
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Application No.: US13201482Application Date: 2010-02-05
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Publication No.: US08759341B2Publication Date: 2014-06-24
- Inventor: Martin Michels , Markus Follmann , Alexandros Vakalopoulos , Katja Zimmermann , Mario Lobell , Nicole Teusch , Shendong Yuan
- Applicant: Martin Michels , Markus Follmann , Alexandros Vakalopoulos , Katja Zimmermann , Mario Lobell , Nicole Teusch , Shendong Yuan
- Applicant Address: DE Monheim
- Assignee: Bayer Intellectual Property GmbH
- Current Assignee: Bayer Intellectual Property GmbH
- Current Assignee Address: DE Monheim
- International Application: PCT/EP2010/000718 WO 20100205
- International Announcement: WO2010/094405 WO 20100826
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D471/04 ; C07D491/048 ; C07D491/147 ; C07D491/153 ; C07D495/04 ; C07D498/14
Abstract:
This invention relates to novel bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.
Public/Granted literature
- US20120035409A1 BI- AND TRICYCLIC INDAZOLE-SUBSTITUTED 1,4-DIHYDROPYRIDINE DERIVATIVES AND USES THEREOF Public/Granted day:2012-02-09
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