Invention Grant
- Patent Title: Co-crystals and pharmaceutical compositions comprising the same
- Patent Title (中): 包含其的共晶体和药物组合物
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Application No.: US12528977Application Date: 2008-02-27
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Publication No.: US08759353B2Publication Date: 2014-06-24
- Inventor: Patrick R. Connelly , Irina Kadiyala , Kathy Stavropoulos , Yuegang Zhang , Steven C. Johnston , Govinda Rao Bhisetti , Valdas Jurkauskas , Peter Rose
- Applicant: Patrick R. Connelly , Irina Kadiyala , Kathy Stavropoulos , Yuegang Zhang , Steven C. Johnston , Govinda Rao Bhisetti , Valdas Jurkauskas , Peter Rose
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Honigman Miller Schwartz and Cohn
- Agent Kathryn D. Soulier; Jonathan P. O'Brien
- International Application: PCT/US2008/002568 WO 20080227
- International Announcement: WO2008/106151 WO 20080904
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61P31/14
Abstract:
The invention relates to compositions and co-crystals each comprising VX-950 and a co-crystal former selected from the group consisting of 4-hydroxybenzoic acid, 4-amino salicylic acid, phenylalanine, threonline, tartaric acid, adipic acid, succinic acetate, proline, methyl 4-hydroxybenzoate, anthranilic acid, and d-Biotin. Also within the scope of this invention are methods of making and using the same.
Public/Granted literature
- US20110059987A1 Co-Crystals and Pharmaceutical Compositions Comprising the Same Public/Granted day:2011-03-10
Information query
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