Invention Grant
- Patent Title: Inhibitors of fatty acid binding protein (FABP)
- Patent Title (中): 脂肪酸结合蛋白（FABP）抑制剂
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Application No.: US13499135Application Date: 2010-10-01
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Publication No.: US08759357B2Publication Date: 2014-06-24
- Inventor: Gerald W. Shipps, Jr. , Clifford C. Cheng , Xioahua Huang , Abdelghani Achab , Peter Orth , Johannes H. Voigt
- Applicant: Gerald W. Shipps, Jr. , Clifford C. Cheng , Xioahua Huang , Abdelghani Achab , Peter Orth , Johannes H. Voigt
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Anna L. Cocuzzo; Catherine D. Fitch
- International Application: PCT/US2010/051070 WO 20101001
- International Announcement: WO2011/043994 WO 20110414
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D471/00 ; C07D487/00 ; C07D491/00
Abstract:
The present invention relates to novel heterocyclic compounds as Fatty Acid Binding Protein (FABP) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the present invention is shown below:
Public/Granted literature
- US20120190696A1 INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) Public/Granted day:2012-07-26
Information query
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