Invention Grant
US08759369B2 Inhalable solid amorphous particles comprising tiotropium bromide and a co-solid
有权
包含噻托溴铵和共固体的可吸入固体无定形颗粒
- Patent Title: Inhalable solid amorphous particles comprising tiotropium bromide and a co-solid
- Patent Title (中): 包含噻托溴铵和共固体的可吸入固体无定形颗粒
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Application No.: US12668546Application Date: 2008-07-03
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Publication No.: US08759369B2Publication Date: 2014-06-24
- Inventor: Xian-Ming Zeng
- Applicant: Xian-Ming Zeng
- Applicant Address: GB London
- Assignee: Norton Healthcare Ltd.
- Current Assignee: Norton Healthcare Ltd.
- Current Assignee Address: GB London
- Agency: RatnerPrestia
- Priority: GB0716026.0 20070816
- International Application: PCT/GB2008/002294 WO 20080703
- International Announcement: WO2009/007687 WO 20090115
- Main IPC: A61K31/46
- IPC: A61K31/46 ; A61K9/16 ; A61K9/19 ; A61K9/48 ; A61M15/00 ; A61P11/06 ; A61P11/08
Abstract:
An inhalable medicament is provided, in particular a new solid-state form of tiotropium bromide. The medicament can be in the form of solid amorphous particles containing an intimate admixture of tiotropium bromide together with a pharmaceutically acceptable co-solid having a glass transition temperature of at least −50° C., such as a sugar and/or sugar alcohol.
Public/Granted literature
- US20100326437A1 INHALABLE MEDICAMENT Public/Granted day:2010-12-30
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