Invention Grant
US08759370B2 O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders
有权
O-甲基化雷帕霉素衍生物用于缓解和抑制淋巴组织增生性疾病
- Patent Title: O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders
- Patent Title (中): O-甲基化雷帕霉素衍生物用于缓解和抑制淋巴组织增生性疾病
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Application No.: US12797085Application Date: 2010-06-09
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Publication No.: US08759370B2Publication Date: 2014-06-24
- Inventor: Mariusz A. Wasik , Leslie M. Shaw
- Applicant: Mariusz A. Wasik , Leslie M. Shaw
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Saul Ewing, LLP
- Agent Kathryn Doyle
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/66
Abstract:
The present invention relates to methods of alleviating and inhibiting a lymphoproliferative disorder in a mammal, the method comprising administering one or more rapamycin derivatives (including rapamycin) to the mammal. Further, the invention provides a method for identifying agents which are useful for alleviating and inhibiting a lymphoproliferative disorders, as well as a method for identifying agents which are capable of inhibiting metastasis of lymphatic tumors in a mammal.
Public/Granted literature
- US20110104304A1 O-Methylated Rapamycin Derivatives For Alleviation And Inhibition Of Lymphoproliferative Disorders Public/Granted day:2011-05-05
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