Invention Grant
US08759404B2 Intravenous propofol emulsion compositions having preservative efficacy
有权
具有防腐功效的静脉内异丙酚乳剂组合物
- Patent Title: Intravenous propofol emulsion compositions having preservative efficacy
- Patent Title (中): 具有防腐功效的静脉内异丙酚乳剂组合物
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Application No.: US11714061Application Date: 2007-03-02
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Publication No.: US08759404B2Publication Date: 2014-06-24
- Inventor: Gautam Vinod Daftary , Srikanth Annappa Pai , Girish Narasimha Shanbhag , Sangeeta Hanurmesh Rivankar
- Applicant: Gautam Vinod Daftary , Srikanth Annappa Pai , Girish Narasimha Shanbhag , Sangeeta Hanurmesh Rivankar
- Applicant Address: IN Mumbai
- Assignee: Bharat Serums & Vaccines Ltd.
- Current Assignee: Bharat Serums & Vaccines Ltd.
- Current Assignee Address: IN Mumbai
- Agency: Thorpe North & Western LLP
- Priority: IN906/MUM/2005 20050805
- Main IPC: A61K31/05
- IPC: A61K31/05
Abstract:
The invention discloses a stable intravenous Propofol oil-in-water emulsion composition having mixed preservatives of low toxicity that is capable of withstanding accidental contamination of bacteria and fungi. The preservative system employed comprising of monoglyceryl ester of lauric acid (Monolaurin) and a member selected from (a) capric acid and/or its soluble alkaline salts or its monoglyceryl ester (Monocaprin); (b) edetate; and (c) capric acid and/or its soluble alkaline salts or its monoglyceryl ester (Monocaprin) and edetate.
Public/Granted literature
- US20070249730A1 Intravenous Propofol emulsion compositions having preservative efficacy Public/Granted day:2007-10-25
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