Invention Grant
- Patent Title: Protecting group for indole group, nucleic acid-synthesizing amidite and nucleic acid-synthesizing method
- Patent Title (中): 吲哚基保护基，核酸合成酰胺和核酸合成方法
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Application No.: US12950836Application Date: 2010-11-19
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Publication No.: US08759502B2Publication Date: 2014-06-24
- Inventor: Tsuyoshi Fujihara
- Applicant: Tsuyoshi Fujihara
- Applicant Address: GB Ledbury
- Assignee: Apta Biosciences Ltd.
- Current Assignee: Apta Biosciences Ltd.
- Current Assignee Address: GB Ledbury
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2009-262124 20091117
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C07H19/04 ; C07H19/16 ; C07H19/23 ; C07H19/207
Abstract:
A protecting group for 1-nitrogen atom of an indole group including a sulfonylethyl carbamate group, wherein the protecting group is represented by the following General Formula (I) and capable of being removed from the 1-nitrogen atom of the indole group in an aprotic solvent: where R represents an alkyl group, a derivative of the alkyl group, a phenyl group or a derivative of the phenyl group.
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