Invention Grant
US08759526B2 Dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes—useful or detection or quantification of desirable target molecules
有权
染料，复合染料和寡核苷酸或包含这种染料的多核苷酸 - 可用或检测或定量所需的靶分子
- Patent Title: Dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes—useful or detection or quantification of desirable target molecules
- Patent Title (中): 染料，复合染料和寡核苷酸或包含这种染料的多核苷酸 - 可用或检测或定量所需的靶分子
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Application No.: US12456515Application Date: 2009-06-17
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Publication No.: US08759526B2Publication Date: 2014-06-24
- Inventor: Yuejun Xiang , Praveen Pande , Rajesh Khazanchi , Elazar Rabbani , Dakai Liu , Wei Cheng
- Applicant: Yuejun Xiang , Praveen Pande , Rajesh Khazanchi , Elazar Rabbani , Dakai Liu , Wei Cheng
- Applicant Address: US NY Parmingdale
- Assignee: Enzo Life Sciences, Inc.
- Current Assignee: Enzo Life Sciences, Inc.
- Current Assignee Address: US NY Parmingdale
- Agent Anna D. DiGabriele Petti, Esq.
- Main IPC: C07D215/38
- IPC: C07D215/38
Abstract:
The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties.
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