Invention Grant
- Patent Title: Process for the preparation of thyroid hormones and salts thereof
- Patent Title (中): 制备甲状腺激素及其盐的方法
-
Application No.: US13515712Application Date: 2010-12-17
-
Publication No.: US08759572B2Publication Date: 2014-06-24
- Inventor: Carlo Felice Viscardi , Enrico Cappelletti , Laura Galimberti , Sonia Gazzetto , Loredana Sini
- Applicant: Carlo Felice Viscardi , Enrico Cappelletti , Laura Galimberti , Sonia Gazzetto , Loredana Sini
- Applicant Address: IT Milan
- Assignee: Bracco Imaging S.p.A.
- Current Assignee: Bracco Imaging S.p.A.
- Current Assignee Address: IT Milan
- Agent M. Caragh Noone
- Priority: EP09179805 20091218
- International Application: PCT/EP2010/070118 WO 20101217
- International Announcement: WO2011/073409 WO 20110623
- Main IPC: C07C229/36
- IPC: C07C229/36
Abstract:
The present invention generally refers to a process for the preparation of L-thyroxine derivatives. More in particular, the present invention relates to a iodination reaction of an aromatic derivative with an appropriate iodinating agent, so to afford the related iodinated compound as disodium salt, which may represent a useful intermediate for the synthesis of the L-thyroxine mono-sodium salt, and the free form thereof.
Public/Granted literature
- US20120296113A1 Process For The Preparation Of Thyroid Hormones And Salts Thereof Public/Granted day:2012-11-22
Information query
