Invention Grant
US08759573B2 Method for preparing optionally substituted p-hydroxymandelic compounds and derivatives thereof
有权
制备任选取代的对羟基扁桃酸化合物及其衍生物的方法
- Patent Title: Method for preparing optionally substituted p-hydroxymandelic compounds and derivatives thereof
- Patent Title (中): 制备任选取代的对羟基扁桃酸化合物及其衍生物的方法
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Application No.: US12682837Application Date: 2008-12-09
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Publication No.: US08759573B2Publication Date: 2014-06-24
- Inventor: Bruno Heinisch , Pascal Pitiot , Jean-Louis Grieneisen
- Applicant: Bruno Heinisch , Pascal Pitiot , Jean-Louis Grieneisen
- Applicant Address: FR Aubervilliers
- Assignee: Rhodia Operations
- Current Assignee: Rhodia Operations
- Current Assignee Address: FR Aubervilliers
- Agency: Hunton & Williams LLP
- Priority: FR0708823 20071218
- International Application: PCT/EP2008/067107 WO 20081209
- International Announcement: WO2009/077383 WO 20090625
- Main IPC: C07C59/00
- IPC: C07C59/00 ; C07C65/21
Abstract:
The invention relates to a method for preparing optionally substituted P-hydroxymandelic compounds and derivatives thereof. The method for preparing the mandelic compounds of the invention comprises condensing in water, in the presence of an alkaline agent, an aromatic compound bearing at least one hydroxyl group and having a free para position, with glycoxylic acid, wherein said method is characterised in that said reaction is carried out in a piston-flow reactor.
Public/Granted literature
- US20110009664A1 METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF Public/Granted day:2011-01-13
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