A hand-held controller for operating a remote vehicle includes a controller body having right and left grips, a first set of input devices are disposed in a left control zone adjacent the left grip, and a second set of input devices are disposed in a right control zone adjacent the right grip. The first set of input devices includes a first analog joystick, a 4-way directional control, and a left rocker control. The second set of input devices includes a second analog joystick, an array of at least four buttons, and a right rocker control. The hand-held controller also includes a mode changer disposed on the controller body and configured to receive an input to change between two or more function modes. Each function mode assigns different functions to one or more of the input devices.