Headsets with multi-color ribbon cable and related systems and methods of manufacture are provided. A representative audio headset includes: a ribbon cable having a body and multiple elongated conductors, the body being formed of electrically insulating material and extending between a connector end an earpiece end, the body having a first side and an opposing second side, the insulating material exhibiting a first color, the multiple elongated conductors being embedded in the body; a connector attached to the connector end and electrically coupled to the conductors; an earpiece connected to the earpiece end and electrically coupled to the conductors; and dye bonded with the insulating material at the second side of the body such that the second side of the body exhibits a second color different from the first color.