The disclosure provides a device and method for disconnecting a download channel of a hand-held terminal. The device comprises: a connection/disconnection unit (308), which comprises a fuse module (308-2) and a fusing module (308-4), arranged between a download connection point (302) and a microprocessor (306); when no downloading is needed by the hand-held terminal, the fusing module (308-4) is provided with a level signal through the download connection point, and switch characteristics of a triode or an MOSFET in the fusing module (308-4) are utilized, to control the connection/disconnection of the download channel between the download connection point (302) and the microprocessor (306), thus avoiding generation of new download channel.