Invention Grant
- Patent Title: Method and apparatus for the dissolution and filtration of a hyperpolarized agent with a neutral dissolution media
- Patent Title (中): 用中性溶出介质溶解和过滤超极化剂的方法和装置
-
Application No.: US12106570Application Date: 2008-04-21
-
Publication No.: US08763410B2Publication Date: 2014-07-01
- Inventor: David Brandon Whitt , Andrew Michael Leach , Peter Miller , Eric Telfeyan
- Applicant: David Brandon Whitt , Andrew Michael Leach , Peter Miller , Eric Telfeyan
- Applicant Address: US NY Niskayuna
- Assignee: General Electric Company
- Current Assignee: General Electric Company
- Current Assignee Address: US NY Niskayuna
- Agent Joseph J. Christian
- Main IPC: F25B19/00
- IPC: F25B19/00 ; A61B5/055

Abstract:
Methods and apparatuses that facilitate dissolving a hyperpolarized agent within a polarizer and transporting it to a receiver is provided. The methods include delivering water to a hyperpolarized agent contained within a polarizer, forming a hyperpolarized aqueous solution, transporting the aqueous solution through a fluid path system out of the polarizer, filtering the aqueous solution through a partical size exclusion filter to a receiver, and modifying the pH of the filtered hyperpolarized aquous solution with a dissolution medium contained in the receiver. Also disclosed herein are apparatuses for dissolving a hyperpolarized agent comprising a vial for containing a hyperpolarized imaging agent therein, a dissolution fluid path, a delivery fluid path, a particle size exclusion filter, and a receiver connected to the particle size exclusion filter and positioned to receive the filtered aqueous solution of the hyperpolarized imaging agent.
Public/Granted literature
Information query