Invention Grant
US08765119B2 Treating amyotrophic lateral sclerosis (ALS)with isolated aldehyde dehydrogenase-positive umbilical cord blood cells
有权
用分离的醛脱氢酶阳性脐带血细胞治疗肌萎缩性侧索硬化（ALS）
- Patent Title: Treating amyotrophic lateral sclerosis (ALS)with isolated aldehyde dehydrogenase-positive umbilical cord blood cells
- Patent Title (中): 用分离的醛脱氢酶阳性脐带血细胞治疗肌萎缩性侧索硬化（ALS）
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Application No.: US10908322Application Date: 2005-05-06
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Publication No.: US08765119B2Publication Date: 2014-07-01
- Inventor: Svitlana Garbuzova-Davis , Andrew Balber , Cyndy Davis-Sanberg , Tracy Gentry , Nicole Kuzmin-Nichols , Paul R Sanberg , Alison Willing
- Applicant: Svitlana Garbuzova-Davis , Andrew Balber , Cyndy Davis-Sanberg , Tracy Gentry , Nicole Kuzmin-Nichols , Paul R Sanberg , Alison Willing
- Applicant Address: US FL Tampa US FL Tampa US NC Durham
- Assignee: University of South Florida,Saneron CCEL Therapeutics, Inc.,StemCo Biomedical, Inc.
- Current Assignee: University of South Florida,Saneron CCEL Therapeutics, Inc.,StemCo Biomedical, Inc.
- Current Assignee Address: US FL Tampa US FL Tampa US NC Durham
- Agency: Smith & Hopen, P.A.
- Agent Robert J. Varkonyi
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K35/28 ; A61K35/48 ; A61K35/12 ; A61K35/50 ; A61K35/30 ; A61K9/00 ; C12N5/0789 ; C12N5/071 ; C12N5/074 ; C12N5/0775
Abstract:
A method of treating a patient with a neurodegenerative disease, such as ALS, using progenitor cells isolated from human umbilical cord blood. Non-invasive transplantation of aldehyde dehydrogenase (ALDH+) expressing progenitor cells provides cell replacement and protection of motor neurons.
Public/Granted literature
- US20050249708A1 Cerebral Intraventricular Transplantation as Method of Treating Amyotrophic Lateral Sclerosis (ALS) Public/Granted day:2005-11-10
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