Invention Grant
- Patent Title: Treatment of vocal cords with autologous dermal fibroblast formulation
- Patent Title (中): 用自体真皮成纤维细胞制剂治疗声带
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Application No.: US13879606Application Date: 2011-10-14
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Publication No.: US08765121B2Publication Date: 2014-07-01
- Inventor: John Maslowski
- Applicant: John Maslowski
- Applicant Address: US PA Exton
- Assignee: Fibrocell Technologies, Inc.
- Current Assignee: Fibrocell Technologies, Inc.
- Current Assignee Address: US PA Exton
- Agency: Pepper Hamilton, LLP
- International Application: PCT/US2011/056303 WO 20111014
- International Announcement: WO2012/051505 WO 20120419
- Main IPC: A01N63/00
- IPC: A01N63/00

Abstract:
Dosage units consist of an autologous cell therapy product composed of fibroblasts grown for each individual to be treated for augmentation or regeneration of vocal cords. The suspension of autologous fibroblasts, grown from a biopsy of each individual's own buccal mucosa or skin using current good manufacturing practices (CGMP) and standard tissue culture procedures, is supplied in vials containing cryopreserved fibroblasts or precursors thereof, having a purity of at least 98% fibroblasts and a viability of at least 85%, for administration of from one to six mL, preferably two mL administered three times approximately three to six weeks apart, of cells at a concentration of from 1.0-2.0×107 cells/mL.
Public/Granted literature
- US20130224160A1 Treatment of Vocal Cords with Autologous Dermal Fibroblast Formulation Public/Granted day:2013-08-29
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