Invention Grant
- Patent Title: Methods and compositions for liposomal formulation of antigens and uses thereof
- Patent Title (中): 抗体脂质体制剂的方法和组合物及其用途
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Application No.: US12720592Application Date: 2010-03-09
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Publication No.: US08765171B2Publication Date: 2014-07-01
- Inventor: Gary Fujii , Francis C. Szoka, Jr. , Douglas S. Watson
- Applicant: Gary Fujii , Francis C. Szoka, Jr. , Douglas S. Watson
- Applicant Address: US CA Oakland US CA Rancho Dominquez
- Assignee: The Regents of the University of California,Molecular Express, Inc.
- Current Assignee: The Regents of the University of California,Molecular Express, Inc.
- Current Assignee Address: US CA Oakland US CA Rancho Dominquez
- Agency: Acuity Law Group, P.C.
- Agent Michael A. Whittaker
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K39/00 ; A61K39/385 ; C07J9/00 ; A61P37/04
Abstract:
The present invention relates to liposomal vaccine compositions, methods for the manufacture thereof, and methods for the use thereof to stimulate an immune response in an animal. These compositions comprise dimyristoylphosphatidylcholine (“DMPC”); either dimyristoylphosphatidylglycerol (“DMPG”) or dimyristoyltrimethylammonium propane (“DMTAP”) or both DMPC and DMTAP; and at least one sterol derivative providing a covalent anchor for one or more immunogenic polypeptide(s) or carbohydrate(s).
Public/Granted literature
- US20100226973A1 METHODS AND COMPOSITIONS FOR LIPOSOMAL FORMULATION OF ANTIGENS AND USES THEREOF Public/Granted day:2010-09-09
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