Invention Grant
- Patent Title: Use of synthetic scaffolds for the production of biosynthetic pathway products
- Patent Title (中): 使用合成支架生产生物合成途径产品
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Application No.: US12918725Application Date: 2009-02-26
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Publication No.: US08765403B2Publication Date: 2014-07-01
- Inventor: John E. Dueber , Jay D. Keasling , Gabriel C. Wu , Ghulam Reza Khan Malmirchegini
- Applicant: John E. Dueber , Jay D. Keasling , Gabriel C. Wu , Ghulam Reza Khan Malmirchegini
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis LLP
- Agent Paula A. Borden
- International Application: PCT/US2009/035274 WO 20090226
- International Announcement: WO2009/108774 WO 20090903
- Main IPC: C12P1/00
- IPC: C12P1/00 ; C12P7/00 ; C07H21/00 ; C12N1/21 ; C12N5/10 ; C12N9/00 ; C12P21/00
Abstract:
The present invention provides methods of producing a product or product precursor of a biosynthetic pathway in a genetically modified host cell. The present invention also provides genetically modified host cells comprising nucleic acids encoding a scaffold polypeptide and nucleic acids comprising nucleotide sequences encoding two or more enzymes in a biosynthetic pathway. The present invention further provides nucleic acids comprising nucleotide sequences encoding scaffold polypeptides, for use in a subject method.
Public/Granted literature
- US20110008829A1 Use of Synthetic Scaffolds for the Production of Biosynthetic Pathway Products Public/Granted day:2011-01-13
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