Invention Grant
- Patent Title: Use of molecular chaperones for the enhanced production of secreted, recombinant proteins in mammalian cells
-
Application No.: US13799564Application Date: 2013-03-13
-
Publication No.: US08765466B2Publication Date: 2014-07-01
- Inventor: Sham-Yuen Chan , Hsinyi Yvette Tang , Yiwen Tao , Yongjian Wu , Ruth Kelly
- Applicant: Bayer Pharmaceuticals Corporation
- Applicant Address: US CA Berkeley
- Assignee: Bayer Pharmaceuticals Corporation
- Current Assignee: Bayer Pharmaceuticals Corporation
- Current Assignee Address: US CA Berkeley
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/10 ; C12N5/071
Abstract:
The present invention relates to a method for increased production of a secreted, recombinant protein product through the introduction of molecular chaperones in a mammalian host cell. The present invention also relates to a mammalian host cell with enhanced expression of a secreted recombinant protein product by coexpressing at least one chaperone protein.
Public/Granted literature
Information query
