Invention Grant
US08765470B2 Reprogramming immortalized B-cells to induced pluripotent stem cells
有权
将永生化的B细胞重编程为诱导多能干细胞
- Patent Title: Reprogramming immortalized B-cells to induced pluripotent stem cells
- Patent Title (中): 将永生化的B细胞重编程为诱导多能干细胞
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Application No.: US13197529Application Date: 2011-08-03
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Publication No.: US08765470B2Publication Date: 2014-07-01
- Inventor: James Thomson , Deepika Rajesh , Sarah Jane Dickerson , Amanda Mack , Michael Miller
- Applicant: James Thomson , Deepika Rajesh , Sarah Jane Dickerson , Amanda Mack , Michael Miller
- Applicant Address: US WI Madison
- Assignee: Cellular Dynamics International, Inc.
- Current Assignee: Cellular Dynamics International, Inc.
- Current Assignee Address: US WI Madison
- Agency: Parker Highlander PLLC
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/63 ; C12N15/85
Abstract:
Methods and composition for providing induced pluripotent stem (iPS) cells are provided. For example, in certain aspects methods including reprogramming B lymphocytes transformed by episomal vectors such as Epstein-Barr virus-based vectors are described. Furthermore, the invention provides induced pluripotent stem cells essentially free of exogenous elements and having B cell immunoglobin variable region rearrangement.
Public/Granted literature
- US20120058562A1 REPROGRAMMING IMMORTALIZED B CELLS Public/Granted day:2012-03-08
Information query
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