Invention Grant
- Patent Title: Adenovirus dodecahedron particles for delivery of pharmaceutical agents
- Patent Title (中): 用于递送药剂的腺病毒十二面体颗粒
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Application No.: US13263632Application Date: 2010-04-09
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Publication No.: US08765666B2Publication Date: 2014-07-01
- Inventor: Ewa Szolajska , Jadwiga Chroboczek , Monika Zochowska
- Applicant: Ewa Szolajska , Jadwiga Chroboczek , Monika Zochowska
- Applicant Address: PL Warszawa
- Assignee: Instytut Bio chemii i Biofizki PAN
- Current Assignee: Instytut Bio chemii i Biofizki PAN
- Current Assignee Address: PL Warszawa
- Agency: Walker & Jocke
- Agent Christopher L. Parmelee
- Priority: PL387780 20090410
- International Application: PCT/PL2010/000026 WO 20100409
- International Announcement: WO2010/117287 WO 20101014
- Main IPC: A61K38/14
- IPC: A61K38/14 ; A61K35/76 ; A61P35/00 ; C07K14/075 ; C07K17/06

Abstract:
The embodiment of the invention is a virus-like particle vector, a process for the manufacture thereof, use of the virus-like particle vector and a pharmaceutical composition, which contains the virus-like particle vector. The vector is intended for the delivery of therapeutic agents into specific mammalian tissues, especially low molecular weight agents, in particular low molecular weight anti-cancer drugs into cancer tissues. More specifically, the invention relates to the virus-like particle vector, which constitutes an adenoviral dodecahedron with the therapeutic substance encapsulated or covalently linked.
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