Invention Grant
US08765700B2 Topical administrations of antisense compounds to VLA-4 for the treatment of respiratory conditions
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用于治疗呼吸道疾病的VLA-4反义化合物的局部给药
- Patent Title: Topical administrations of antisense compounds to VLA-4 for the treatment of respiratory conditions
- Patent Title (中): 用于治疗呼吸道疾病的VLA-4反义化合物的局部给药
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Application No.: US11666001Application Date: 2005-10-20
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Publication No.: US08765700B2Publication Date: 2014-07-01
- Inventor: George Tachas , James G. Karras , Susan Gregory , Jeffrey R. Crosby , Kenneth W. Dobie , Frank C. Bennett
- Applicant: George Tachas , James G. Karras , Susan Gregory , Jeffrey R. Crosby , Kenneth W. Dobie , Frank C. Bennett
- Applicant Address: AU
- Assignee: Antisense Therapeutics Ltd.
- Current Assignee: Antisense Therapeutics Ltd.
- Current Assignee Address: AU
- Agency: Quine Intellectual Property Law Group P.C.
- International Application: PCT/AU2005/001634 WO 20051020
- International Announcement: WO2006/086821 WO 20060824
- Main IPC: C12N15/11
- IPC: C12N15/11

Abstract:
A method for the treatment and/or prophylaxis of an animal having a respiratory disease or condition associated with airway hyperresponsiveness, eosinophilia, neutrophilia, leukocytes or overproduction of mucus and/or with the expression of integrin α4 comprising administering to the animal a composition comprising from. 0.001 to 1000 μg per kg body weight of the animal of an antisense compound targeted to a nucleic acid molecule encoding integrin α4.
Public/Granted literature
- US20090029931A1 Topical administrations of antisense compounds to vla-4 for the treatment of respiratory conditions Public/Granted day:2009-01-29
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