Invention Grant
- Patent Title: Modification of MYD88 splicing using modified oligonucleotides
- Patent Title (中): 使用修饰的寡核苷酸修饰MYD88剪接
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Application No.: US12963303Application Date: 2010-12-08
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Publication No.: US08765703B2Publication Date: 2014-07-01
- Inventor: Timothy Vickers , Nicholas M. Dean
- Applicant: Timothy Vickers , Nicholas M. Dean
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Isis Pharmaceuticals, Inc. Patent Dept.
- Main IPC: C12N15/11
- IPC: C12N15/11
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of MyD88. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding MyD88. Methods of using these compounds for modulation of MyD88 expression and for treatment of diseases associated with expression of MyD88 are provided.
Public/Granted literature
- US20110092573A1 MODIFICATION OF MYD88 SPLICING USING MODIFIED OLIGONUCLEOTIDES Public/Granted day:2011-04-21
Information query
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