Invention Grant
- Patent Title: Macrocyclic compounds and their use as kinase inhibitors
- Patent Title (中): 大环化合物及其作为激酶抑制剂的用途
-
Application No.: US12692078Application Date: 2010-01-22
-
Publication No.: US08765727B2Publication Date: 2014-07-01
- Inventor: Andrew Paul Combs , Richard B. Sparks , Eddy Wai Tsun Yue , Hao Feng , Michael Jason Bower , Wenyu Zhu
- Applicant: Andrew Paul Combs , Richard B. Sparks , Eddy Wai Tsun Yue , Hao Feng , Michael Jason Bower , Wenyu Zhu
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Pepper Hamilton LLP
- Main IPC: A61K31/33
- IPC: A61K31/33 ; C07D487/00
Abstract:
The present invention relates to macrocyclic compounds of Formula I: or pharmaceutically acceptable salts thereof or quaternary ammonium salts thereof wherein constituent members are provided hereinwith, as well as their compositions and methods of use, which are JAK/ALK inhibitors useful in the treatment of JAK/ALK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer.
Public/Granted literature
- US20110251215A9 MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS Public/Granted day:2011-10-13
Information query
