Invention Grant
- Patent Title: Heteroaryls and uses thereof
- Patent Title (中): 杂芳基及其用途
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Application No.: US13272413Application Date: 2011-10-13
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Publication No.: US08765746B2Publication Date: 2014-07-01
- Inventor: Brian S. Freeze , Masaaki Hirose , Hong Myung Lee , Todd B. Sells , Zhan Shi , Leo R. Takaoka , Stepan Vyskocil , Tianlin Xu
- Applicant: Brian S. Freeze , Masaaki Hirose , Hong Myung Lee , Todd B. Sells , Zhan Shi , Leo R. Takaoka , Stepan Vyskocil , Tianlin Xu
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Choate, Hall & Stewart LLP
- Agent Andrea L. C. Reid; Daniel A. Klein
- Main IPC: C07D409/04
- IPC: C07D409/04 ; C07D409/14 ; C07D417/04 ; A61K31/427 ; A61K31/4196 ; A61K31/5377
Abstract:
This invention provides compounds of formula I-A or I-B: wherein HY, G1, G2, R2, R12, W1, W2, n, and Ring A are as described in the specification. The compounds are inhibitors of PI3K and/or mTor and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
Public/Granted literature
- US20120214794A1 HETEROARYLS AND USES THEREOF Public/Granted day:2012-08-23
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