Invention Grant
- Patent Title: Piperazine compound having a PGDS inhibitory effect
- Patent Title (中): 具有PGDS抑制作用的哌嗪化合物
-
Application No.: US13522605Application Date: 2011-01-19
-
Publication No.: US08765750B2Publication Date: 2014-07-01
- Inventor: Yoshihiro Urade , Makoto Kitade , Kazuhiko Shigeno , Keiko Yamane , Katsunao Tanaka
- Applicant: Yoshihiro Urade , Makoto Kitade , Kazuhiko Shigeno , Keiko Yamane , Katsunao Tanaka
- Applicant Address: JP Tokyo
- Assignee: Taiho Pharmaceutical Co., Ltd.
- Current Assignee: Taiho Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: JP2010-012501 20100122
- International Application: PCT/JP2011/050840 WO 20110119
- International Announcement: WO2011/090062 WO 20110728
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/5377 ; C07D401/14 ; C07D413/14 ; C07D403/14

Abstract:
The present invention provides a piperazine compound represented by Formula (I) or a salt thereof, wherein X represents CH or an N atom; R1 represents C1-6 alkyl; R2 represents C1-6 alkyl that may have one or more substituents, C2-6 alkenyl that may have one or more substituents, —(C═O)—N(R3)(R4), or —(C═O)—OR5, R3 and R4 are the same or different, and each represents hydrogen or C1-6 alkyl that may have one or more substituents; or R3 and R4, taken together with a nitrogen atom to which R3 and R4 are attached, may form a saturated heterocyclic group; and R5 represents hydrogen or C1-6 alkyl that may have one or more substituents or aralkyl.
Public/Granted literature
- US20120309760A1 PIPERAZINE COMPOUND HAVING A PGDS INHIBITORY EFFECT Public/Granted day:2012-12-06
Information query
IPC分类: