Invention Grant
- Patent Title: 3-hydroxyisothiazole 1-oxide derivatives
- Patent Title (中): 3-羟基异噻唑1-氧化物衍生物
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Application No.: US13841710Application Date: 2013-03-15
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Publication No.: US08765752B2Publication Date: 2014-07-01
- Inventor: Munetaka Ohkouchi
- Applicant: Mochida Pharmaceutical Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Mochida Pharmaceutical Co., Ltd.
- Current Assignee: Mochida Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2011-100203 20110427; JP2011-144937 20110629; JP2011-185337 20110826
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A01N43/58 ; A01N43/60 ; A61K31/50 ; A61K31/495 ; A01N43/42 ; A61K31/44 ; A61K31/47 ; A01N43/40 ; A01N43/78 ; A61K31/425 ; A01N43/80

Abstract:
[Object]To provide a GPR40 activating agent containing, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the compound or the salt, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases.[Means of Solving the Problem]A compound of Formula (I): (where p is 0 to 4; j is 0 to 2; k is 0 to 1; a ring A is an aryl group, a heterocyclic group, a cycroalkyl group, a cycroalkenyl group, a spirocyclic group; a ring B is an aryl group, a heteroaryl group; X is O or —NR7—; and R1 to R7 and L are specific groups), a salt of the compound, or a solvate of the compound or the salt.
Public/Granted literature
- US20130217690A1 NOVEL 3-HYDROXYISOTHIAZOLE 1-OXIDE DERIVATIVES Public/Granted day:2013-08-22
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