Invention Grant
- Patent Title: Substituted piperazines as CGRP antagonists
- Patent Title (中): 取代的哌嗪作为CGRP拮抗剂
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Application No.: US13322264Application Date: 2010-06-02
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Publication No.: US08765763B2Publication Date: 2014-07-01
- Inventor: Alexander Dreyer , Henri Doods , Kai Gerlach , Dirk Gottschling , Annekatrin Heimann , Stephan Georg Mueller , Klaus Rudolf , Gerhard Schaenzle
- Applicant: Alexander Dreyer , Henri Doods , Kai Gerlach , Dirk Gottschling , Annekatrin Heimann , Stephan Georg Mueller , Klaus Rudolf , Gerhard Schaenzle
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Alan R. Stempel
- Priority: EP09162068 20090605; EP09174459 20091029
- International Application: PCT/EP2010/057693 WO 20100602
- International Announcement: WO2010/139717 WO 20101209
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/499

Abstract:
The present invention relates to new CGRP-antagonists of general formula I wherein R1, R2, R3, Ra, Rb, Rc, X, Y and Z are defined as mentioned hereinafter, the individual diastereomers, the individual enantiomers and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, the use thereof and processes for the preparation thereof.
Public/Granted literature
- US20120196872A1 NEW 5-ALKYNYL-PYRIDINES Public/Granted day:2012-08-02
Information query
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