Invention Grant
- Patent Title: Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
- Patent Title (中): 嘌呤衍生物用于治疗过敏性，炎性和感染性疾病
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Application No.: US13058470Application Date: 2009-08-07
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Publication No.: US08765772B2Publication Date: 2014-07-01
- Inventor: Keith Biggadike , Diane Mary Coe , Xiao Qing Lewell , Charlotte Jane Mitchell , Stephen Allan Smith , Naimisha Trivedi
- Applicant: Keith Biggadike , Diane Mary Coe , Xiao Qing Lewell , Charlotte Jane Mitchell , Stephen Allan Smith , Naimisha Trivedi
- Applicant Address: US PA Philadelphia
- Assignee: GlaxoSmithKline LLC
- Current Assignee: GlaxoSmithKline LLC
- Current Assignee Address: US PA Philadelphia
- Agent Kathryn L. Coulter
- International Application: PCT/EP2009/060265 WO 20090807
- International Announcement: WO2010/018133 WO 20100218
- Main IPC: A61K31/522
- IPC: A61K31/522 ; C07D473/34
Abstract:
The present invention relates to compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
Public/Granted literature
- US20110229500A1 PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES Public/Granted day:2011-09-22
Information query
IPC分类:
