Invention Grant
US08765791B2 Method of treating cancer using a neuropeptide Y 5R (NP Y5R) antagonist
有权
使用神经肽Y 5R（NP Y5R）拮抗剂治疗癌症的方法
- Patent Title: Method of treating cancer using a neuropeptide Y 5R (NP Y5R) antagonist
- Patent Title (中): 使用神经肽Y 5R（NP Y5R）拮抗剂治疗癌症的方法
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Application No.: US12921959Application Date: 2009-03-10
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Publication No.: US08765791B2Publication Date: 2014-07-01
- Inventor: Guohua Pan
- Applicant: Guohua Pan
- Applicant Address: CA Toronto
- Assignee: University Health Network
- Current Assignee: University Health Network
- Current Assignee Address: CA Toronto
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- International Application: PCT/CA2009/000286 WO 20090310
- International Announcement: WO2009/111868 WO 20090917
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/44 ; A01N43/56 ; A61K31/415 ; A01N43/08 ; A61K31/34 ; A01N43/38 ; A61K31/40 ; A01N43/42 ; C07D405/00 ; C07D307/88 ; C07D237/02 ; C07D471/10 ; A61K31/4412 ; A61K31/4355
Abstract:
The present invention relates to methods for treating cancer by administering a therapeutically effective amount of compound of formula (I), such as selective NPY5R antagonist MK-0557 (trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H), 1′-cyclohexane]-4′-carboxamide), or a pharmaceutically acceptable salt thereof, to a subject in need thereof The methods can further comprise administering a chemotherapeutic agent to the subject in need thereof.
Public/Granted literature
- US20110112102A1 METHOD OF TREATING CANCER USING A NEUROPEPTIDE Y 5R (NP Y5R) ANTAGONIST Public/Granted day:2011-05-12
Information query
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