Invention Grant
- Patent Title: Streptospirole derivatives
- Patent Title (中): 链球菌衍生物
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Application No.: US13056751Application Date: 2009-07-16
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Publication No.: US08765799B2Publication Date: 2014-07-01
- Inventor: Cosima Dufour-Schroif , Joachim Wink , Martin Gerlitz , Hélène Olivan , Michael Kurz
- Applicant: Cosima Dufour-Schroif , Joachim Wink , Martin Gerlitz , Hélène Olivan , Michael Kurz
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP08167138 20080731
- International Application: PCT/EP2009/005155 WO 20090716
- International Announcement: WO2010/012381 WO 20100204
- Main IPC: A61K31/407
- IPC: A61K31/407 ; C07D491/107 ; C07D498/10
Abstract:
The invention relates to streptospirole derivatives of the general formula (I), wherein R1, R2, R3, X1, X2, Y1 and Y2 are as defined herein, a process for the preparation of said compounds by fermenting the microorganism Streptomyces sp. ST 108140 (DSM 19369) and optionally derivatizing the compounds produced by said microorganism, a pharmaceutical composition comprising at least one compound of the formula (I), and the use of a compound of the formula (I) for the preparation of a medicament for the treatment and/or prophylaxis of bacterial infections.
Public/Granted literature
- US20110295009A1 STREPTOSPIROLE DERIVATIVES Public/Granted day:2011-12-01
Information query
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