Invention Grant
US08765800B2 Crystalline (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine
有权
结晶（1r，4r）-6'-氟-N，N-二甲基-4-苯基-4'，9'-二氢-3'H-螺[环己烷-1,1'-吡喃并[3,4，b ]吲哚] -4-胺
![Crystalline (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine](/docs/US/2014-07-01/US08765800B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine
- Patent Title (中): 结晶（1r，4r）-6'-氟-N，N-二甲基-4-苯基-4'，9'-二氢-3'H-螺[环己烷-1,1'-吡喃并[3,4，b ]吲哚] -4-胺
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Application No.: US13835298Application Date: 2013-03-15
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Publication No.: US08765800B2Publication Date: 2014-07-01
- Inventor: Michael Gruss , Stefan Kluge , Sefan Pruehs
- Applicant: Gruenenthal GmbH
- Applicant Address: DE Aachen
- Assignee: Gruenenthal GmbH
- Current Assignee: Gruenenthal GmbH
- Current Assignee Address: DE Aachen
- Agency: Crowell & Moring LLP
- Priority: EP11005587 20110708
- Main IPC: C07D491/052
- IPC: C07D491/052 ; A61K31/407 ; C07D491/107
![Crystalline (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine](/abs-image/US/2014/07/01/US08765800B2/abs.jpg.150x150.jpg)
Abstract:
Crystalline forms of (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine, pharmaceutical compositions and medicaments comprising these crystalline modifications, the use of these modifications as well as a process for the enrichment of such crystalline modifications.
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