Invention Grant
- Patent Title: Tumor necrosis factor inhibitors
- Patent Title (中): 肿瘤坏死因子抑制剂
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Application No.: US13654765Application Date: 2012-10-18
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Publication No.: US08765810B2Publication Date: 2014-07-01
- Inventor: Mark I. Greene , Ramachandran Murali , Xin Cheng , Raphael Ottenbrite , Yingxin Xiaio
- Applicant: The Trustees Of The University Of Pennsylvania , Cephalon, Inc.
- Applicant Address: US PA Philadelphia US DE Wilmingotn
- Assignee: The Trustees Of The University Of Pennsylvania,Cephalon, Inc.
- Current Assignee: The Trustees Of The University Of Pennsylvania,Cephalon, Inc.
- Current Assignee Address: US PA Philadelphia US DE Wilmingotn
- Agency: Baker & Hostetler LLP
- Main IPC: A61K31/15
- IPC: A61K31/15 ; A61K31/352 ; A61K31/365 ; C07C251/86
Abstract:
The present invention is directed to compounds that are allosteric inhibitors of tumor necrosis factor receptor I, compositions comprising such compounds, and methods of using such compounds and compositions thereof in the treatment of TNF-α mediated conditions.
Public/Granted literature
- US20130072562A1 TUMOR NECROSIS FACTOR INHIBITORS Public/Granted day:2013-03-21
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