Invention Grant
- Patent Title: N-hydroxyformamide derivative and medicament containing same
- Patent Title (中): N-羟基甲酰胺衍生物和含有它们的药物
-
Application No.: US13809027Application Date: 2011-07-05
-
Publication No.: US08765814B2Publication Date: 2014-07-01
- Inventor: Kentaro Kawai , Shigeru Miyamoto , Masanao Shimano , Makoto Haino
- Applicant: Kentaro Kawai , Shigeru Miyamoto , Masanao Shimano , Makoto Haino
- Applicant Address: JP Tokyo
- Assignee: Kaken Pharmaceutical Co., Ltd.
- Current Assignee: Kaken Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Nixon & Vanderhye P.C.
- Priority: JP2010-156025 20100708
- International Application: PCT/JP2011/065317 WO 20110705
- International Announcement: WO2012/005229 WO 20120112
- Main IPC: A01N41/12
- IPC: A01N41/12 ; A61K31/16
Abstract:
A compound represented by the following general formula (I) which has ADAM17 inhibitory activity, or a salt thereof, or a solvate thereof: wherein X represents a phenylene group; Y represents a hydrogen atom, —(CH2)mR1 or the like; R1 represents —NR5COR2, —NR5SO2R2 or —NR3R4; R2 represents a C1-C6 alkyl group, an aryl group, or a C1-C6 alkoxy group; R3 and R4 represent a C1-C6 alkyl group and the like; R5 represents a hydrogen atom or a C1-C6 alkyl group or the like; m indicates an integer of from 0 to 4; and Z represents a hydrogen atom or a C1-C6 alkyl group.
Public/Granted literature
- US20130131180A1 N-HYDROXYFORMAMIDE DERIVATIVE AND MEDICAMENT CONTAINING SAME Public/Granted day:2013-05-23
Information query
