Invention Grant
US08765953B2 Compounds and methods for the treatment of pain and other diseases
有权
用于治疗疼痛和其他疾病的化合物和方法
- Patent Title: Compounds and methods for the treatment of pain and other diseases
- Patent Title (中): 用于治疗疼痛和其他疾病的化合物和方法
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Application No.: US13141384Application Date: 2009-12-21
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Publication No.: US08765953B2Publication Date: 2014-07-01
- Inventor: Irving Sucholeiki
- Applicant: Irving Sucholeiki
- Applicant Address: US MA Winchester
- Assignee: Aquilus Pharmaceuticals, Inc.
- Current Assignee: Aquilus Pharmaceuticals, Inc.
- Current Assignee Address: US MA Winchester
- Agency: Burns & Levinson LLP
- Agent Jacob N. Erlich
- International Application: PCT/US2009/069005 WO 20091221
- International Announcement: WO2010/075287 WO 20100701
- Main IPC: C07D221/02
- IPC: C07D221/02 ; C07D209/04 ; C07D209/20
Abstract:
The present invention relates generally to alkyne containing pharmaceutical agents, and in particular, to phenylethynyl-thiophene based metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of MMP inhibiting compounds that exhibit increased potency, metabolic stability and/or reduced toxicity in relation to currently known MMP inhibitors for the treatment of pain and other diseases such as cancer. Additionally, the present invention relates to methods for treating pain in a patient comprising administering to the patient a pain-reducing effective amount of a present compound.
Public/Granted literature
- US20110257222A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES Public/Granted day:2011-10-20
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