Invention Grant
- Patent Title: Process for the iodination of phenolic derivatives
- Patent Title (中): 酚类衍生物碘化方法
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Application No.: US13702223Application Date: 2011-06-09
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Publication No.: US08766003B2Publication Date: 2014-07-01
- Inventor: Attilio Citterio , Elisa Battistini , Davide Belnome , Federica Buonsanti , Luciano Lattuada , Gabriella Leonardi , Fulvio Uggeri , Evelin Vignale , Massimo Visigalli
- Applicant: Attilio Citterio , Elisa Battistini , Davide Belnome , Federica Buonsanti , Luciano Lattuada , Gabriella Leonardi , Fulvio Uggeri , Evelin Vignale , Massimo Visigalli
- Applicant Address: IT Milan
- Assignee: Bracco Imaging S.p.A.
- Current Assignee: Bracco Imaging S.p.A.
- Current Assignee Address: IT Milan
- Agent M. Caragh Noone
- Priority: EP10165485 20100610
- International Application: PCT/EP2011/059594 WO 20110609
- International Announcement: WO2011/154500 WO 20111215
- Main IPC: C07C231/12
- IPC: C07C231/12 ; C07C231/14 ; C07B39/00

Abstract:
The present invention relates to a process for the preparation of iodinated phenols; in particular; it relates to a process including the direct iodination, with suitably activated iodine, of 3,5-disubstituted phenol compounds to the corresponding 3,5-disubstituted-2,4,6-triiodophenols, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves.
Public/Granted literature
- US20130072719A1 Process For The Iodination Of Phenolic Derivatives Public/Granted day:2013-03-21
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