A Zantedeschia variety designated 110067-52451 is disclosed. The invention relates to the seeds of Zantedeschia 110067-52451, the plants of Zantedeschia 110067-52451, plant parts of Zantedeschia variety 110067-52451, and methods for producing a Zantedeschia plant produced by crossing Zantedeschia 110067-52451 with itself or with another Zantedeschia variety. The invention also relates to methods for producing a Zantedeschia plant containing in its genetic material one or more genes or transgenes and the transgenic Zantedeschia plants and plant parts produced by those methods. This invention also relates to Zantedeschia varieties, or breeding varieties, and plant parts derived from Zantedeschia 110067-52451, methods for producing other Zantedeschia varieties, hybrids, or plant parts derived from Zantedeschia 110067-52451, and to the Zantedeschia plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid Zantedeschia seeds, plants, and plant parts produced by crossing the Zantedeschia 110067-52451 with another Zantedeschia variety.