An information processing apparatus and an information processing method including a deformation shape model generation unit configured to generate, from information about a first shape and a first position of a feature region in a target object under a first deformation condition, a deformation of the first shape with the position of the feature region as a reference as a model, and a deformation estimation unit configured to, based on information about a second shape and a second position corresponding to the feature region in the target object under the second deformation condition, align the first position with the second position to estimate deformation from the first shape to the second shape using the model.