An optical cross-connect assembly and method are provided that are suitable for use in both small-scale and large-scale applications. The optical cross-connect assembly comprises first and second stacks of multi-optical fiber connector modules that are configured to orthogonally mechanically couple with one another such that the optical ports of each of the connector modules of the first stack are optically aligned with respective optical ports of all of the connector modules of the second stack, and such that the optical ports of each of the connector modules of the second stack are optically aligned with respective optical ports of all of the connector modules of the first stack.