A motor-driven compressor is to be mounted to a first mounting of a vehicle. The compressor includes a housing having therein a compression mechanism that is electrically powered to draw fluid into the housing for compression and to discharge the compressed fluid out of the housing, and a second mounting for securing the housing to the first mounting. The second mounting includes a first cylindrical member, a damping member made of a resin and provided between the first cylindrical member and the housing, a first fastening member extending through the first cylindrical member and the damping member for securing the first cylindrical member and the damping member to the housing, and a second fastening member inserted through the first cylindrical member for securing the first cylindrical member to the first mounting.